Cartridges

Room temperature stable, fully sealed cartridges perform multiple tests simultaneously.

Enables assessment of coagulopathy in the perioperative setting.

Ideal for use in cardiovascular and major orthopedic procedures.

Runs 4 tests simultaneously; provides 6 actionable results.

Rapid start: <1 minute; complete results in 15 minutes or less.

The QPlus Cartridge is a multi-channel cartridge to be used with the Quantra^® Hemostasis Analyzer.

Rapidly Identifies:

Clot initiation
Likelihood of heparin influence
Fibrinogen contribution to clot stiffness
Platelet contribution to clot stiffness

hemosonics quantra hemostasis analyzer qplus analyzer

Intended for in vitro diagnostic use to evaluate the viscoelastic properties of whole blood.
Requires a sample of 3mL or more of citrated venous whole blood collected in an evacuated tube.

Indications for Use

The Quantra QPlus System is composed of the Quantra Hemostasis Analyzer, QPlus Cartridge, and Quantra Quality Controls Level 1 and 2. The Quantra QPlus System is intended for in vitro diagnostic use.

The Quantra Hemostasis Analyzer uses Sonic Estimation of Elasticity via Resonance (SEER) Sonorheometry, an ultrasound-based technology, to measure the shear modulus of whole blood during coagulation. The QPlus Cartridge is a multi-channel cartridge that provides semi-quantitative indications of the coagulation state of a 3.2% citrated venous whole blood sample. The QPlus Cartridge includes tests to assess coagulation characteristics via the intrinsic pathway, via the extrinsic pathway, and includes tests with a heparin neutralizer.

The system is intended to be used by trained professionals at the point-of-care and in clinical laboratories to evaluate the viscoelastic properties of whole blood by means of the following functional parameters: Clot Time (CT), Clot Time with Heparinase (CTH), Clot Stiffness (CS), Fibrinogen Contribution to Clot Stiffness (FCS), Platelet Contribution to Clot Stiffness (PCS) and Clot Time Ratio (CTR).

The Quantra QPlus System is indicated for the evaluation of blood coagulation in perioperative patients age 18 years and older to assess possible hypocoagulable and hypercoagulable conditions in cardiovascular or major orthopedic surgeries before, during, and following the procedure.

Results obtained with the Quantra QPlus System should not be the sole basis for patient diagnosis.

For prescription use only.

*Rx Only. Please consult the Quantra User Manual and/or cartridge Instructions for Use for complete information.

QPlus Cartridge Measurements

Parameter	Units	Description	Measurement
Clot Time (CT)	Seconds	Clot time in citrated whole blood.	Clot time measured in Channel #1 with activator of the intrinsic pathway (kaolin).
Heparinase Clot Time (CTH)	Seconds	Clot time in citrated whole blood with heparin neutralization.	Clot time measured in Channel #2 with activator of the intrinsic pathway (kaolin) and heparinase.
Clot Time Ratio (CTR)	No Units	The CTR parameter may indicate the prolongation of the intrinsic pathway clotting time that is likely due to the influence of unfractionated heparin. CTR values are not directly correlated with heparin levels in the sample; if CTR is > 1.4, it is only indicative of heparin in the sample.	Calculated as the ratio of clot time values of Channel #1 over Channel #2 (CT/CTH).
Clot Stiffness (CS)	hecto Pascals (hPa)	Stiffness of the whole blood clot.	Clot stiffness measured in Channel #3 with an activator of the extrinsic pathway (thromboplastin) and heparin inhibitor (polybrene).
Fibrinogen Contribution to Clot Stiffness (FCS)	hecto Pascals (hPa)	Contribution of functional fibrinogen to overall clot stiffness.	Clot stiffness measured from Channel #4 with an activator of the extrinsic pathway (thromboplastin) and heparin inhibitor (polybrene) and platelet inhibitor (abciximab).
Platelet Contribution to Clot Stiffness (PCS)	hecto Pascals (hPa)	Contribution of platelet activity to overall clot stiffness.	Calculated by subtracting clot stiffness value of Channel #4 from Channel #3.