Charlottesville, VA – June 6, 2016 – HemoSonics today announced that a paper introducing its novel QuantraTM Hemostasis Analyzer was published online in Anesthesia and Analgesia. The paper, A Novel Device for the Evaluation of Hemostatic Function in Critical Care Settings, introduces the Quantra and its initial Surgical Cartridge, which is intended for monitoring coagulation during and after major surgical procedures with potential applications in other critical care settings. The Quantra system was designed to address the market gap for a rapid, comprehensive, easy-to-use, near-patient coagulation analyzer.
The paper describes key findings from comparative studies using a research use only (RUO) version of the Quantra System. The Quantra reliably characterized coagulation factor function, and quantified functional fibrinogen, platelet function, and overall clot stiffness as well as the presence of residual heparin anticoagulation. Dysfunctions of these coagulation components are the primary sources of bleeding during and after major surgery. In addition, all Quantra results were obtained within 15 minutes of test initiation, an extremely rapid response for such comprehensive information.
The study demonstrated highly reproducible results, with coefficients of variation for each output parameter ranging from 2.5% to 8.8%. In addition, the Quantra displayed a wide dynamic range for measuring clot stiffness, enabling measurement of very soft clots that are often associated with clinical bleeding. Furthermore, Quantra results correlated strongly with existing laboratory tests such as Clauss Fibrinogen.
“These findings demonstrate that the Quantra provides a rapid and comprehensive view of a patient’s coagulation status, something currently unavailable today,” said Francesco Viola, Chief Scientific Officer of HemoSonics and lead author on the paper. “These findings suggest that the Quantra and the Surgical Cartridge have the potential to provide clinicians with much-needed information to aid in the diagnosis and treatment of critical bleeding.”
EA Ferrante, KR Blasier, TB Givens, CA Lloyd, TJ Fischer, F Viola, A Novel Device for the Evaluation of Hemostatic Function in Critical Care Setting, Anesth Analg. 2016; doi: 10.1213/ANE.0000000000001413